Premature Ovarian Failure (POI) Treatment in Kolkata — Options Still Exist
Being diagnosed with premature ovarian insufficiency (POI) before you expected — in your 20s or 30s — can feel like your world has been turned upside down. At Maatritva IVF in Newtown, Kolkata, Dr. Ankita Mandal approaches this diagnosis with both clinical expertise and deep compassion. Parenthood may still be possible, and we will explore every realistic path with you.
Understanding This Condition
Premature Ovarian Insufficiency (POI), previously called premature ovarian failure, occurs when the ovaries stop functioning normally before age 40 — causing irregular or absent periods, low estrogen, elevated FSH, and significantly reduced fertility. Unlike natural menopause, POI can be intermittent — occasional spontaneous ovulation still occurs in some women. Causes include genetic (Turner syndrome, FMR1 premutation), autoimmune destruction of ovarian tissue, previous chemotherapy/radiation, or idiopathic (unknown).
Symptoms & Diagnosis
Women under 40 with irregular or absent periods, hot flashes, night sweats, or vaginal dryness; those with FSH above 25 IU/L on two tests taken a month apart; women with a family history of early menopause; those diagnosed via karyotyping with Turner syndrome or other chromosomal causes.
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Our doctors can evaluate your history and discuss the options.
Treatment Options
- 1Step 1: Hormonal confirmation — FSH, LH, estradiol, AMH (usually very low or undetectable), antral follicle count
- 2Step 2: Genetic testing — karyotype, FMR1 premutation testing
- 3Step 3: Autoimmune panel — thyroid, adrenal, and ovarian antibodies
- 4Step 4: Hormone replacement therapy (HRT) — essential for bone and heart health while planning fertility
- 5Step 5: If own eggs still possible (intermittent function) — aggressive monitoring for spontaneous follicle development
- 6Step 6: Donor egg IVF — generally the most likely route to pregnancy for women with POI; success varies with individual factors
Discuss Your Case With A Specialist
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