PCOS and Infertility Treatment in Kolkata — Getting Pregnant with PCOS Is Possible

Understanding This Condition

Polycystic Ovary Syndrome (PCOS) is a hormonal condition where the ovaries produce excess androgens (male hormones), disrupting ovulation. Instead of releasing one mature egg each month, the ovaries develop multiple small, immature follicles — the 'cysts' seen on ultrasound — none of which fully release. This irregular or absent ovulation is the primary reason PCOS causes infertility. PCOS also affects insulin sensitivity, making weight management harder and compounding hormonal imbalance.

Symptoms & Diagnosis

Women with irregular or absent periods, excess facial or body hair (hirsutism), acne, unexplained weight gain, ultrasound showing polycystic ovaries, who have been trying to conceive for 6–12 months without success. Also women already diagnosed with PCOS who are planning pregnancy and want to optimise their chances.

Treatment Options

• 1Step 1: Detailed hormonal panel — LH, FSH, AMH, testosterone, DHEAS, fasting insulin, prolactin
• 2Step 2: Pelvic ultrasound — follicle count, ovarian volume, endometrial thickness
• 3Step 3: Lifestyle intervention — targeted diet, weight management, inositol supplementation (may help insulin sensitivity and ovulation in some women; evidence is mixed)
• 4Step 4: Ovulation induction — Letrozole (first-line) or Clomiphene with ultrasound monitoring
• 5Step 5: If ovulation induction fails (3–4 cycles) — IUI with monitored ovarian stimulation
• 6Step 6: If IUI fails — tailored IVF with PCOS-specific stimulation protocol to prevent OHSS