Azoospermia Treatment in Kolkata — Zero Sperm Does Not Mean Zero Hope
Being told there is no sperm in your ejaculate is one of the most unexpected and difficult diagnoses a man can receive. At Maatritva IVF in Newtown, Kolkata, we want you to know before anything else: in a significant proportion of azoospermia cases, biological fatherhood is still achievable — through surgical sperm retrieval and ICSI. Let's understand your specific case before drawing any conclusions.
Understanding This Condition
Azoospermia is the complete absence of sperm in the ejaculate. It affects approximately 1% of all men and 10–15% of men with infertility. There are two types: (1) Obstructive azoospermia — sperm is being produced but cannot reach the ejaculate due to blockage (blocked vas deferens, post-vasectomy, epididymal obstruction). Sperm retrieval success is ~90% in this type. (2) Non-obstructive azoospermia (NOA) — the testes are producing little or no sperm due to testicular failure, hormonal issues, or genetic factors. Micro-TESE retrieval success in NOA is 40–60%.
Symptoms & Diagnosis
Men with zero sperm on two separate semen analyses (collected 4–6 weeks apart), those with azoospermia after vasectomy, men with a history of mumps orchitis, testicular torsion, chemotherapy, undescended testes, chromosomal abnormalities (Klinefelter syndrome), or Y-chromosome microdeletions.
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Treatment Options
- 1Step 1: Repeat semen analysis + post-ejaculate urine analysis to confirm azoospermia
- 2Step 2: Hormonal panel — FSH, LH, testosterone, inhibin B (distinguish obstructive from non-obstructive)
- 3Step 3: Genetic testing — karyotype, Y-chromosome microdeletion screening
- 4Step 4: Testicular ultrasound — assess testicular volume and architecture
- 5Step 5: TESA/PESA (obstructive) or micro-TESE (non-obstructive) for sperm retrieval
- 6Step 6: Retrieved sperm used directly for ICSI with partner's eggs, or cryopreserved for future use
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