Medical Blog
IUI vs IVF — How to Decide Which to Try First
IUI or IVF first? It is one of the most common questions at Maatritva IVF. The answer is never one-size-fits-all — but there is a clear, evidence-based framework Dr. Ankita uses to guide every couple.
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Dr. Ankita Mandal
MBBS (SCB Medical College, Cuttack), MS — OBG (RIMS, Ranchi), Fellowship in Infertility, Advanced Diploma in Reproductive Medicine & ART (KIEL, Germany)
IUI is appropriate when:
- Both fallopian tubes are open
- Sperm count and motility are mild-to-moderately reduced (count >5 million motile)
- Ovulation can be stimulated or timed effectively
- The woman is under 35 with good ovarian reserve
- The diagnosis is unexplained infertility and you have time to try this gentler step
- Cost is a significant consideration (IUI costs ₹8,000–₹20,000 vs ₹1.2L–₹2.5L for IVF)
IVF is recommended directly when:
- Both fallopian tubes are blocked
- Severe male factor infertility (requires ICSI)
- Female age is 38 or older
- Failed 3–4 IUI cycles
- Advanced endometriosis (Stage III–IV)
- Very low AMH or poor ovarian reserve
- PGT (genetic testing of embryos) is needed
Indicative figures from published data (general figures, not this clinic's results; they vary widely with age and diagnosis):
- IUI success rate: 15–22% per cycle
- IVF success rate: 55–70% per cycle (under 35)
Skipping IUI to go straight to IVF is sometimes the right decision — especially for older women where time is critical. Spending several months on IUI cycles with a low chance of success may reduce later IVF chances because of age-related decline.
Dr. Ankita discusses this framework openly with every couple. She considers your specific diagnosis, age, ovarian reserve, sperm quality, budget, and emotional readiness before recommending a path.
Want to Discuss This With A Doctor?
Contact the clinic to enquire about a confidential consultation.
There is no universally right answer — but there IS a right answer for your specific situation. Book a consultation at Maatritva IVF, Newtown Kolkata and let Dr. Ankita map your personal fertility roadmap.